Three-level clustered data commonly occur in social and behavioral research and bolia outlet gent are prominently analyzed using multilevel modeling.The influence of the clustering on estimation results is assessed with the intraclass correlation coefficients (ICCs), which indicate the fraction of variance in the outcome located at each higher leve
abc material The effectiveness of topical application of various drugs in ophthalmology is no more than 3 % due to the presence of anatomical and physiological barriers.The therapeutic effect accomplishment is possible with increasing concentration or multiplicity of drug use.The article presents the results of the development of a new type of ther
Abstract Background Tumour progression involves a series of phenotypic changes to cancer cells, each of which presents therapeutic targets.Here, using techniques adapted from microbial experimental evolution, we investigate the evolution of tumour spreading - a precursor for metastasis and tissue invasion - in environments with varied resource supp